My advice would hinge on how you get along with the missus in general. If there's a lot of control and you find that overbearing, then maybe you push for solo trips. If that's not the case and her concern is about the travel and enclosed spaces, then I'd really recommend respecting those wishes. 1. because of course there is enhanced risk and it sounds like she's being perfectly reasonable, and 2. because she's your wife. And I wouldn't make "no one from a VMB trip report has said they got the virus" be a definitive sample size of course or a marker for the risk. I hear you on wanting to go. I typically go 4x a year (usually solo), but I've taken this whole thing very seriously and simply would not enjoy myself at all in current Vegas and I'd be a hypocrite to my missus if I did!