My last trip was semi-solo and the next one will also be semi-solo, 1st week with a friend, 2nd week solo. I do like solo traveling in general, but as a female I don't consider Las Vegas the best destination to go alone tbh. It's just that since my first trip to Vegas (with BF at that time) a couple of years ago, I fell in love with the city and don't want to go anywhere else. And I prefer to travel alone, than with just someone.
But in other cities you find a lot of people traveling on their own and there are places where you can meet and hang out, like parks, the beach, backpackers places or local bars/pubs/coffeeshops where you see the same hotel neighbors again or the people you were on the same flight with. Easy enough to pick out the ones who travel solo and like to have a conversation or hang out together. I mean, I'm quite outgoing and usually have no problem getting to know new people, but in Vegas everything is so huge and you don't automatically meet the same people again at your hotel -bar or -restaurant, as the night before.
Also, to travel on your own as a woman to for example a city like Barcelona or
Paris is completely normal, you can walk around with a city map in your hand, visit the musea and other cultural things etc and have a drink at the bar of your hotel. But for some reason, when you are going to a place like Sin City (what's in a name?!), people (men of course lol) sometimes get the wrong impression and seem to think you're looking for a sexual adventure or financial benefit or something.
But anyway... that all said, I would completely recommend it haha!

For all the reasons already mentioned in the other replies.
What I do is, I try to hook-up with other solo travelers / Vegas lovers which I met on previous travels or online on sites like this one for example. Coming holiday I will hook-up with a friend from the States for a couple of days and we will make a trip to Laughlin. I will also join some get-togethers posted on the forum and organise one or two of my own. And on the other days when I'm alone, I will probably hang out at the pool and spa, go shopping, take a long bath back in my room (don't have that luxury at home unfortunately) and join some larger poker tournements in the evenings. Things I prefer to do on my own anyway.
And I will sure keep an eye on this thread as well, cause I saw already a lot of great tips flying around!
Enjoy your trip!!
